翻訳と辞書
Words near each other
・ Leusden
・ Leukoplakia
・ Leukoplakia with tylosis and esophageal carcinoma
・ Leukopoiesis
・ Leukoreduction
・ Leukorrhea
・ Leukostasis
・ Leukotriene
・ Leukotriene A4
・ Leukotriene A4 synthase
・ Leukotriene B4
・ Leukotriene B4 receptor
・ Leukotriene B4 receptor 1
・ Leukotriene B4 receptor 2
・ Leukotriene C4
Leukotriene C4 synthase
・ Leukotriene C4 synthase deficiency
・ Leukotriene D4
・ Leukotriene E4
・ Leukotriene receptor
・ Leukotriene receptor antagonist-associated Churg–Strauss syndrome
・ Leukotriene-A4 hydrolase
・ Leukotriene-B4 20-monooxygenase
・ Leukotriene-C4 hydrolase
・ Leukotriene-C4 synthase
・ Leukotriene-E4 20-monooxygenase
・ Leul Abate
・ Leulinghem
・ Leulinghen-Bernes
・ Leulumoega


Dictionary Lists
翻訳と辞書 辞書検索 [ 開発暫定版 ]
スポンサード リンク

Leukotriene C4 synthase : ウィキペディア英語版
Leukotriene C4 synthase

Leukotriene C4 synthase is an enzyme that in humans is encoded by the ''LTC4S'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4056 )
The protein encoded by this gene, LTC4S (or glutathione S-transferase II) is an enzyme that converts leukotriene A4 and glutathione to create leukotriene C4. This is a member of MAPEG family of transmembrane proteins. A trimer of Leukotriene C4 synthase is localized on the outer nuclear membrane and endoplasmic reticulum, where it forms a complex with 5-Lipoxygenase-activating protein. This protein is remotely related to microsomal glutathione S-transferase.
== Function ==

The MAPEG (Membrane-Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Leukotriene C4 synthase」の詳細全文を読む



スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース

Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.